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Research Description:
My primary research interest is
to determine the genetic etiology of colon cancer. Research objectives are to
characterize the prevalence of known genetic factors in a high-risk population
(under 50 or two 1st degree relatives), and to identify novel colon
cancer susceptibility genes, and genetic modifiers by linkage analysis using
large families and sibling pairs with colon cancer. I work with the Pedigree and Population Resource group, to
identify at-risk families, the High-Risk Cancer Clinics, to recruit family
members into research, and the Department of Human Genetics to identify cancer
susceptibility genes.
Research Keywords:
colon cancer; genetics; human
genetics; translational research; inheritance.